Some kind of loading zone or cell code is the cause maybe but Im way to new to modding to know for sure yet. weirdest thing is that if you go all the way west to the Power Plant and save your game with the custom INI file deleted then close the game, reinstall the Custom INI to get all mods that need it working you can then load up the save and there are no issues until about 25% of the way back down the hill. From what I have figured, any mod that needs the Custom INI file will CTD hard anywhere in Nuka-World.